Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639568 | 1.00 | ESRRB (0.49) | ESRRBGPR139KMT2ATSHRACE | |
| SCHEMBL10633562 | 1.00 | ESRRB (0.49) | ESRRBGPR139KMT2ATSHRACE | |
| SCHEMBL18113164 | 0.86 | KMT2A (0.50) | GPR139KMT2AACEALDH1A1MAPT | |
| SCHEMBL10633458 | 0.86 | KMT2A (0.46) | ESRRBKMT2ATSHRACEMME | |
| SCHEMBL10639492 | 0.86 | KMT2A (0.46) | ESRRBKMT2ATSHRACEMME | |
| SCHEMBL15281190 | 0.84 | ESRRB (0.47) | ESRRBGPR139KMT2ATSHRPTGS1 | |
| SCHEMBL10639398 | 0.84 | ADRB2 (0.45) | KMT2AALDH1A1MAPT | |
| SCHEMBL10636996 | 0.84 | ADRB2 (0.45) | KMT2AALDH1A1MAPT | |
| SCHEMBL4918632 | 0.83 | KMT2A (0.45) | GPR139KMT2ATSHRACEMME | |
| SCHEMBL7897731 | 0.83 | GPR139 (0.50) | GPR139KMT2ATSHRACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259465-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1988-03-16 | — | — | EP | claimed |
| WO-1987005328-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-09-11 | — | — | WO | claimed |
| US-5482847-A | Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said trasnformants | MITSUBISHI RAYON CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5476791-A | Reacting thioacetic acid with methyl methacrylate; contacting the propionate with cells of microorganisms to effect biological and asymmetric hydrolysis; extraction; reacting with L-proline | MITSUBISHI RAYON COMPANY, LIMITED (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5308765-A | Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically acitve carboxylic acids and their enantiomeric esters using said transformants | MITSUBISHI RAYON CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0435178-B1 | Process for racemizing optically active carboxylic acid esters | MITSUBISHI RAYON CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| EP-0513806-A1 | Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants | MITSUBISHI RAYON CO., LTD (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-5149855-A | Recomposing, contacting with amine; elipdar aprotic solvent | MITSUBISHI RAYON CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0435178-A1 | Process for racemizing optically active carboxylic acid esters | MITSUBISHI RAYON CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0172614-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID AMIDES | MITSUBISHI RAYON CO., LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |
| EP-0259465-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1988-03-16 | — | — | EP | disclosed |
| WO-1987005328-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-09-11 | — | — | WO | disclosed |
| US-4629701-A | USING A HYDROLASE OR HICROORGANISM IN A CULTURE | MITSUBISHI RAYON COMPANY, LIMITED (JP) | 1986-12-16 | — | — | US | disclosed |