Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949672 | 0.70 | GABRP (0.34) | FKBP5CRBN | |
| SCHEMBL12129960 | 0.68 | — | — | |
| SCHEMBL2916419 | 0.68 | — | — | |
| SCHEMBL3265053 | 0.68 | — | — | |
| SCHEMBL9083443 | 0.68 | FKBP5 (0.34) | FKBP5CRBN | |
| SCHEMBL11226687 | 0.66 | TSHR (0.42) | FKBP5CRBN | |
| SCHEMBL283680 | 0.66 | — | — | |
| SCHEMBL11223666 | 0.66 | TSHR (0.42) | FKBP5CRBN | |
| SCHEMBL283682 | 0.66 | — | — | |
| SCHEMBL283681 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519013-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| US-5334586-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | PROCTER & GAMPLE PHARMACEUTICALS, INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0274158-B1 | Novel heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate matabolism | NORWICH EATON PHARMA (US) | 1994-03-23 | — | — | EP | disclosed |
| US-5071840-A | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |