⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217080 | 0.89 | HTR1A (0.66) | — | |
| SCHEMBL9083462 | 0.88 | HTR1A (0.60) | — | |
| Hydrochloric Acid SCHEMBL9620015 | 0.88 | HTR1A (0.65) | — | |
| SCHEMBL9083448 | 0.85 | HTR1A (0.63) | — | |
| SCHEMBL9082977 | 0.84 | HTR1A (0.60) | — | |
| SCHEMBL9441673 | 0.82 | — | — | |
| SCHEMBL10613018 | 0.81 | — | — | |
| SCHEMBL8823806 | 0.80 | HTR1A (0.57) | — | |
| SCHEMBL9306055 | 0.79 | DRD2 (0.47) | — | |
| SCHEMBL9456624 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510374-A | USEFUL IN TREATMENT OF DISORDERS OF THE SEROTINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-04-23 | — | — | US | disclosed |
| US-5346916-A | FOR TREATING ANIMALS SUFFERING FROM DISORDERS OF THE SEROTONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5314907-A | 3-aminochroan compounds | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| US-5273994-A | Also hydroxy- or alkyl ether-substituted | ADIR ET COMPAGNIE (FR) | 1993-12-28 | — | — | US | disclosed |
| US-5252578-A | Treatment of disorders of teh serotoninergic system | ADIR ET COMPAGNIE (FR) | 1993-10-12 | — | — | US | disclosed |