Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.65 |
| ▸ | PRKCB | P05771 | 4/20 | 0.63 |
| ▸ | PRKCA | P17252 | 4/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.63 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.63 |
| ▸ | PRKCG | P05129 | 3/20 | 0.63 |
| ▸ | PRKCH | P24723 | 3/20 | 0.63 |
| ▸ | PRKCI | P41743 | 3/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085077 | 0.94 | CAMK2D (0.65) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9084298 | 0.93 | PRKCB (0.63) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9084332 | 0.92 | PRKCB (0.65) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9086035 | 0.91 | PRKCB (0.64) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9088345 | 0.90 | PRKCB (0.76) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9087327 | 0.90 | PRKCB (0.63) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9088687 | 0.90 | TDP1 (0.65) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9086927 | 0.90 | PRKCB (0.63) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9087284 | 0.89 | TDP1 (0.63) | CAMK2DPRKCBPRKCAPRKCEPRKD1 | |
| SCHEMBL9087068 | 0.88 | TDP1 (0.71) | CAMK2DPRKCBPRKCAPRKCEPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516915-A | Bis-(1H-indol-3-yl)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |