Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 12/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425521 | 0.93 | NOTUM (0.42) | NOTUMARACACBTAS1R3TAS1R1 | |
| SCHEMBL8424215 | 0.91 | NOTUM (0.42) | NOTUMARACACBTAS1R3TAS1R1 | |
| SCHEMBL8424641 | 0.89 | NOTUM (0.40) | NOTUMARACACBTAS1R3TAS1R1 | |
| SCHEMBL9255706 | 0.87 | NOTUM (0.44) | NOTUMARACACBTAS1R3TAS1R1 | |
| SCHEMBL9253749 | 0.86 | NOTUM (0.43) | NOTUMARACACBTAS1R3TAS1R1 | |
| SCHEMBL8428103 | 0.83 | MTOR (0.32) | — | |
| SCHEMBL8427942 | 0.83 | ALOX5 (0.40) | NOTUMACACB | |
| SCHEMBL8425429 | 0.82 | ACACB (0.41) | NOTUMACACB | |
| SCHEMBL9083674 | 0.78 | NOTUM (0.42) | NOTUMACACBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8428043 | 0.75 | MTOR (0.33) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484933-A | Process for production of fluoroalkane carboxamide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |