Morpheridine

Morpheridine

SCHEMBL908537

CCOC(=O)C1(c2ccccc2)CCN(CCN2CCOCC2)CC1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 8/20 0.76
OPRD1 P41143 6/20 0.76
OPRK1 P41145 6/20 0.76
SLC22A1 O15245 1/20 0.72
SLC6A4 P31645 1/20 0.72
ADRA1A P35348 1/20 0.72
KCNH2 Q12809 1/20 0.72
KCNA3 P22001 3/20 0.71
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
ALDH1A1 P00352 1/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C9 P11712 1/20 0.69
PKM P14618 1/20 0.69
CYP2C19 P33261 1/20 0.69
PRCP P42785 1/20 0.69
TMEM97 Q5BJF2 1/20 0.69
SIGMAR1 Q99720 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11712840 0.88 OPRM1 (0.82) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL11601769 0.87 OPRM1 (0.80) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL11712071 0.87 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL11708747 0.86 KCNA3 (0.80) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL11599945 0.86 OPRM1 (0.78) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Pheneridine SCHEMBL1922392 0.85 KCNA3 (0.86) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Hydrochloric Acid SCHEMBL11603600 0.85 OPRM1 (0.79) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL25431 0.84 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Carperidine SCHEMBL2107753 0.84 OPRM1 (0.74) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL6197539 0.84 KCNA3 (0.77) OPRM1OPRD1OPRK1SLC22A1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213727-A1 DOMINANT-NEGATIVE TUMOR NECROSIS FACTOR ALPHA ADENO-ASSOCIATED VIRUS GENE THERAPY REGENXBIO INC. 2025-07-03 US claimed
CN-119597046-A Real-time control system of micro-reactor for fine chemical industry 南京科技职业学院 2025-03-11 CN claimed
CN-119006599-B Image processing method, device and system for vehicle wheelbase measurement 川开电气有限公司 2025-01-28 CN claimed
US-20240393248-A1 INFORMATION PROCESSING DEVICE, BIOLOGICAL SAMPLE OBSERVATION SYSTEM, AND IMAGE GENERATION METHOD Sony Group Corporation (JP) 2024-11-28 US claimed
CN-119006599-A Image processing method, device and system for vehicle wheelbase measurement 川开电气有限公司 2024-11-22 CN claimed
CN-118915649-A Production process monitoring system based on industrial Internet 无锡学院 2024-11-08 CN claimed
CN-118817022-A Intelligent water level monitoring and predicting method, system, electronic equipment and storage medium 中国建筑第八工程局有限公司 2024-10-22 CN claimed
CN-118798106-A Analog circuit yield optimization method based on freeze thawing Bayesian optimization technology 复旦大学 2024-10-18 CN claimed
CN-118627251-A Method for estimating towing force of unmanned ship and UUV umbilical cable 中国海洋石油集团有限公司 2024-09-10 CN claimed
CN-115396109-B Control method and system for dynamic data authorization based on scenerization 四川中电启明星信息技术有限公司 2024-09-10 CN claimed
WO-2007054378-A1 ANTI-MISUSE MICROPARTICULATE ORAL PHARMACEUTICAL FORM FLAMEL TECHNOLOGIES (FR) 2007-05-18 WO claimed
WO-2006134018-A2 ORAL DOSAGE FORM COMPRISING AN ANTIMISUSE SYSTEM FLAMEL TECHNOLOGIES (FR) 2006-12-21 WO claimed
WO-2006133733-A1 ORAL DOSAGE FORM COMPRISING AN ANTIMISUSE SYSTEM FLAMEL TECHNOLOGIES (FR) 2006-12-21 WO claimed
WO-2006089843-A2 ANTI-MISUSE MICROPARTICULATE ORAL DRUG FORM FLAMEL TECHNOLOGIES (FR) 2006-08-31 WO claimed
EP-1569925-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2005-09-07 EP claimed
WO-2004055003-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2004-07-01 WO claimed
EP-0608893-B1 Compositions for inhibiting the development of tolerance to and/or dependence on an additive substance UNIV VIRGINIA COMMONWEALTH (US) 2001-12-12 EP claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed