Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085697 | 1.00 | NPSR1 (0.34) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL8111844 | 0.84 | NPSR1 (0.33) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL8111842 | 0.84 | NPSR1 (0.33) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL8111818 | 0.84 | TAS1R3 (0.36) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL8111817 | 0.84 | TAS1R3 (0.36) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL5704365 | 0.83 | ALDH1A1 (0.35) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL5704364 | 0.83 | ALDH1A1 (0.35) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL1345391 | 0.82 | CYP2D6 (0.38) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL1345392 | 0.82 | CYP2D6 (0.38) | NPSR1CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL9562436 | 0.82 | CYP2D6 (0.38) | NPSR1CYP2D6CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0544981-A2 | Naphthyridone carboxylic acid derivatives and antibacterial compositions containing them | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |