Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 14/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083975 | 0.89 | DRD2 (0.65) | SLC6A1KDM1ACHRM2CHRM4HTR1A | |
| SCHEMBL32690192 | 0.86 | KDM1A (0.75) | KDM1AFPR2 | |
| SCHEMBL10136829 | 0.86 | KDM1A (0.75) | KDM1AFPR2 | |
| SCHEMBL6867689 | 0.86 | KDM1A (0.74) | KDM1AFPR2 | |
| SCHEMBL13305180 | 0.86 | KDM1A (0.74) | KDM1AFPR2 | |
| SCHEMBL9086491 | 0.86 | FPR2 (0.82) | CHRM2CHRM4HTR1AADRA2ACHRM1 | |
| SCHEMBL6865338 | 0.84 | KDM1A (0.75) | KDM1AFPR2 | |
| Pyrathiazine SCHEMBL2110244 | 0.84 | KDM1A (0.76) | KDM1A | |
| Pyrathiazine SCHEMBL30184095 | 0.84 | KDM1A (0.76) | KDM1A | |
| Pyrathiazine SCHEMBL142434 | 0.83 | KDM1A (0.73) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585314-B1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK AS (DK) | 1996-09-18 | — | — | EP | claimed |