Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 7/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.46 |
| ▸ | CHRNG | P07510 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088720 | 0.91 | CAPN1 (0.53) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| Hydrochloric Acid SCHEMBL9090563 | 0.90 | CAPN1 (0.52) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL9088881 | 0.83 | CAPN1 (0.54) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL7761860 | 0.83 | CAPN1 (0.58) | CAPN1CTSLLMNACTSBCTSG | |
| SCHEMBL7407617 | 0.82 | CAPN1 (0.52) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL7408113 | 0.82 | CAPN1 (0.52) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL9229415 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL7402596 | 0.82 | CAPN1 (0.55) | PLGPRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL7406175 | 0.80 | TSHR (0.57) | PLGPRSS1PRSS2PRSS3CHRND | |
| SCHEMBL7405238 | 0.80 | CAPN1 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556853-A | THIOL PROTEASE INHIBITORS, TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0655447-A1 | Epoxysuccinic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-05-31 | — | — | EP | disclosed |