Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRND | Q07001 | 9/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 5/20 | 0.52 |
| ▸ | CHRNG | P07510 | 5/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9090563 | 0.99 | CAPN1 (0.52) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9088881 | 0.91 | CAPN1 (0.54) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9086642 | 0.91 | PLG (0.48) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7402596 | 0.90 | CAPN1 (0.55) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7761860 | 0.89 | CAPN1 (0.58) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL7408113 | 0.89 | CAPN1 (0.52) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9229415 | 0.89 | CHRNB2 (0.54) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7406175 | 0.89 | TSHR (0.57) | CAPN1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL7405238 | 0.89 | CAPN1 (0.53) | CAPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7762766 | 0.88 | CTSL (0.60) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556853-A | THIOL PROTEASE INHIBITORS, TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0655447-A1 | Epoxysuccinic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-05-31 | — | — | EP | disclosed |