Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.57 |
| ▸ | F2 | P00734 | 6/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.56 |
| ▸ | PLG | P00747 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012310 | 0.90 | F2 (0.55) | TMPRSS11DF2F10PLGCHRM3 | |
| SCHEMBL7586431 | 0.90 | F2 (0.69) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL7341166 | 0.86 | F2 (0.53) | TMPRSS11DF2F10PLGPRSS1 | |
| Trifluoroacetic Acid SCHEMBL9012341 | 0.86 | CHRM3 (0.57) | TMPRSS11DF2CHRM3ITGB3ITGA2B | |
| SCHEMBL7341151 | 0.86 | TMPRSS11D (0.57) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL9085053 | 0.86 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL9085068 | 0.85 | F2 (0.50) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL9088895 | 0.84 | STS (0.54) | TMPRSS11DF2F10PLG | |
| SCHEMBL9087955 | 0.83 | TMPRSS11D (0.50) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL9011944 | 0.82 | TMPRSS11D (0.55) | TMPRSS11DF2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561146-A | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0686642-A2 | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-13 | — | — | EP | disclosed |