Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133239 | 0.79 | MAOA (0.49) | CA12CA9HPGDCASP1ALOX15 | |
| SCHEMBL10227267 | 0.75 | PIM1 (0.52) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL24151117 | 0.75 | ERN1 (0.45) | PIM1HPGDCASP1CES2GALR3 | |
| SCHEMBL27013927 | 0.73 | PIM1 (0.53) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL258689 | 0.71 | PIM1 (0.55) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL8191851 | 0.70 | ERN1 (0.56) | HPGDCASP1CES2GALR3CYP1A2 | |
| SCHEMBL24343629 | 0.69 | PIM1 (0.55) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL2761544 | 0.68 | PIM1 (1.00) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL15168459 | 0.68 | PIM1 (0.48) | PIM1CA12CA9CSNK2A2CSNK2B | |
| SCHEMBL2588529 | 0.68 | PIM1 (0.58) | PIM1CA12CA9CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559231-A | PHOTOCHROMIC, RECORDING MATERIAL, CLOTHING, GLASSES, WINDOWS | TORAY INDUSTRIES, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0358774-B1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5374723-A | Photochromic dyes; resistance to repetition of coloration and discoloration | TORAY INDUSTRIES, INC. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0358774-A1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1990-03-21 | — | — | EP | disclosed |