Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.49 |
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9087955 | 0.92 | TMPRSS11D (0.50) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL9086574 | 0.91 | F2 (0.51) | F2TMPRSS11DCMA1F10PLG | |
| SCHEMBL9085779 | 0.88 | F2 (0.51) | F2TMPRSS11DCMA1F10PLG | |
| SCHEMBL7346744 | 0.88 | F2 (0.54) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL9073567 | 0.86 | F2 (0.51) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL9012124 | 0.84 | ACE (0.48) | F2TMPRSS11DCMA1F10PLG | |
| SCHEMBL9088440 | 0.84 | F2 (0.48) | F2CMA1TACR1ACEPRSS1 | |
| SCHEMBL9012355 | 0.84 | F2 (0.51) | F2TMPRSS11DCMA1F10PLG | |
| SCHEMBL9012346 | 0.84 | F2 (0.51) | F2TMPRSS11DCMA1F10PLG | |
| SCHEMBL9012134 | 0.83 | F2 (0.51) | F2TMPRSS11DCMA1F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686642-A2 | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-13 | — | — | EP | claimed |
| US-5561146-A | Modified guanidino and amidino thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-01 | — | — | US | disclosed |