Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.43 |
| ▸ | PRKCG | P05129 | 5/20 | 0.43 |
| ▸ | PRKCB | P05771 | 5/20 | 0.43 |
| ▸ | PRKCA | P17252 | 5/20 | 0.43 |
| ▸ | PRKCH | P24723 | 5/20 | 0.43 |
| ▸ | PRKCI | P41743 | 5/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9087780 | 0.98 | KCNA3 (0.47) | KCNA3CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL28598940 | 0.84 | PTGS1 (0.48) | KCNA3CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL28393087 | 0.81 | KCNA3 (0.49) | KCNA3CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL2423484 | 0.80 | KCNA3 (0.48) | KCNA3CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL11122104 | 0.79 | ALDH1A1 (0.44) | KCNA3KDM4ECYP1A2PTGS1MEN1 | |
| SCHEMBL29546384 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2D6LMNAKDM4ECYP2C19 | |
| SCHEMBL3994903 | 0.75 | KCNA3 (0.51) | KCNA3CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL115053 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2D6LMNAKDM4ECYP2C19 | |
| SCHEMBL10818956 | 0.74 | ESR1 (0.42) | LMNACYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL96459 | 0.74 | MAPT (0.58) | KCNA3CYP3A4CYP2D6LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565457-A | FOR TREATMENT OF MYOCARDIAL ISCHEMIAS AND CEREBRAL VASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | disclosed |