SCHEMBL9089569

SCHEMBL9089569

O=C(Cl)C1C2OC(C1C(=O)Cl)C(C(=O)Cl)C2C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
GBA1 P04062 2/20 0.30
PPP5C P53041 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2930249 0.73 ALDH1A1 (0.31) TSHR
SCHEMBL3795408 0.73 ALDH1A1 (0.31) TSHR
SCHEMBL3267619 0.71 SUCNR1 (0.40)
SCHEMBL15796345 0.69 TSHR (0.68) TSHRGBA1PPP5C
SCHEMBL12762660 0.67 PPM1B (0.39)
Hydrochloric Acid SCHEMBL9445206 0.67 TSHR (0.65) TSHRPPP5C
SCHEMBL1663988 0.65 TSHR (0.48) TSHRPPP5C
SCHEMBL1763662 0.65
SCHEMBL27685159 0.65
SCHEMBL14275295 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510527-A Acid chloride NITTO DENKO CORPORATION (JP) 1996-04-23 US disclosed
US-5336409-A Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1994-08-09 US disclosed
EP-0556569-A2 Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1993-08-25 EP disclosed