SCHEMBL2930249

SCHEMBL2930249

O=C(Cl)C1C(C(=O)Cl)C1C(=O)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3795408 1.00 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL18784097 0.84 POLB (0.38) ALDH1A1TSHR
SCHEMBL27685159 0.79
SCHEMBL30352474 0.76
SCHEMBL12732736 0.76 POLB (0.38)
SCHEMBL9440339 0.73 POLB (0.42)
SCHEMBL2384920 0.73 GABRR1 (0.30)
SCHEMBL2065772 0.73 GABRR1 (0.30)
SCHEMBL13224121 0.73 GABRR1 (0.30)
SCHEMBL9089569 0.73 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1792894-B1 Contrast agents GE HEALTHCARE AS (NO) 2010-09-22 EP claimed
US-7485753-B2 Contrast agents GE HEALTHCARE AS (NO) 2009-02-03 US claimed
US-20080199402-A1 Contrast Agents GE HEALTHCARE AS (NO) 2008-08-21 US claimed
EP-1792894-A2 Contrast agents GE Healthcare AS (NO) 2007-06-06 EP claimed
EP-1792894-B1 Contrast agents GE HEALTHCARE AS (NO) 2010-09-22 EP disclosed
US-7485753-B2 Contrast agents GE HEALTHCARE AS (NO) 2009-02-03 US disclosed
US-7485753-B2 Contrast agents GE HEALTHCARE AS (NO) 2009-02-03 US disclosed
US-20080199402-A1 Contrast Agents GE HEALTHCARE AS (NO) 2008-08-21 US disclosed
US-20080199402-A1 Contrast Agents GE HEALTHCARE AS (NO) 2008-08-21 US disclosed
EP-1792894-A2 Contrast agents GE Healthcare AS (NO) 2007-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080199402-A1 Contrast Agents PYM1, MIA3, IPO11 ALDH1A1 4426/4885TSHR 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.