Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088981 | 0.95 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9085942 | 0.93 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9087422 | 0.88 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9086832 | 0.88 | AGTR1 (0.54) | AGTR1AGTR2 | |
| Water SCHEMBL9087080 | 0.84 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9089456 | 0.82 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9091277 | 0.82 | AGTR2 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9085910 | 0.82 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9089155 | 0.82 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9086750 | 0.82 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519138-A | ANGIOTENSIN ANTAGONIST | DR. KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0529253-A1 | Phenylalkylderivatives, compounds containing them and process for their fabrication | Dr. Karl Thomae GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |