Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.70 |
| ▸ | DRD4 | P21917 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 3/20 | 0.70 |
| ▸ | DRD1 | P21728 | 2/20 | 0.70 |
| ▸ | DRD5 | P21918 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088460 | 0.96 | DRD2 (0.63) | DRD2DRD4DRD3DRD1DRD5 | |
| Oxalic Acid SCHEMBL7320058 | 0.83 | DRD2 (0.98) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL9089665 | 0.83 | HTR6 (0.52) | DRD2DRD4DRD3DRD1DRD5 | |
| Oxalic Acid SCHEMBL7316564 | 0.82 | DRD2 (0.84) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL9088049 | 0.80 | HTR6 (0.73) | — | |
| SCHEMBL7112194 | 0.79 | DRD2 (0.69) | DRD2DRD4DRD3DRD1DRD5 | |
| Oxalic Acid SCHEMBL7311582 | 0.79 | DRD2 (0.72) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL7310505 | 0.78 | DRD2 (0.81) | DRD2DRD4DRD3DRD1DRD5 | |
| Oxalic Acid SCHEMBL7322376 | 0.78 | DRD2 (0.71) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL7309245 | 0.77 | DRD2 (0.87) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541199-A | DOPAMINE MODULATORS, SCHIZOPHRENIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |