Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850188 | 0.92 | CD274 (0.51) | CD274TDP1DRD2LMNAPAOX | |
| SCHEMBL39934 | 0.91 | CD274 (0.60) | CD274TDP1DRD2CACNA1HSMN1; SMN2 | |
| SCHEMBL13075277 | 0.88 | DRD2 (0.56) | CD274TDP1DRD2CACNA1H | |
| SCHEMBL4118080 | 0.87 | DRD2 (0.49) | TDP1DRD2CACNA1H | |
| SCHEMBL39968 | 0.86 | LMNA (0.58) | CD274DRD2LMNA | |
| SCHEMBL4119702 | 0.86 | EPHX1 (0.49) | TDP1DRD2CACNA1H | |
| SCHEMBL4753694 | 0.84 | CD274 (0.54) | CD274TDP1DRD2CACNA1HSMN1; SMN2 | |
| SCHEMBL16941149 | 0.83 | MEN1 (0.47) | TDP1DRD2CACNA1HSMN1; SMN2LMNA | |
| SCHEMBL4755773 | 0.82 | CD274 (0.55) | CD274TDP1DRD2CACNA1HSMN1; SMN2 | |
| SCHEMBL31301242 | 0.80 | DRD2 (0.63) | CD274TDP1DRD2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099691-B1 | PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS | PROMEGA CORP (US) | 2019-11-20 | — | — | EP | disclosed |
| WO-2015116806-A1 | PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS | PROMEGA CORPORATION (US) | 2015-08-06 | — | — | WO | disclosed |
| US-5561139-A | IMMUNOSUPPRESSANTS; SIDE EFFECT REDUCTION | ABBOTT LABORATORIES (US) | 1996-10-01 | — | — | US | disclosed |
| US-5530120-A | ANALOGS OF ASCOMYCIN AND FK-506 AS IMMUNOSUPPRESSANTS AND-MODULATORS; SIDE EFFECT REDUCTION | ABBOTT LABORATORIES (US) | 1996-06-25 | — | — | US | disclosed |
| WO-1994021634-A1 | SUBSTITUTED ALICYCLIC-ALIPHATIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |