Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 8/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093620 | 0.79 | F2 (0.37) | F2TMPRSS6PRSS1PRSS2PRSS3 | |
| SCHEMBL9095129 | 0.78 | ITGB3 (0.35) | F2 | |
| SCHEMBL9093657 | 0.75 | F2 (0.42) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9093651 | 0.75 | ITGB3 (0.39) | — | |
| SCHEMBL9093809 | 0.74 | ITGB3 (0.36) | F2 | |
| Trifluoroacetic Acid SCHEMBL9093493 | 0.74 | ITGB3 (0.35) | F2TMPRSS6 | |
| SCHEMBL9093514 | 0.73 | ITGB3 (0.42) | — | |
| SCHEMBL9091922 | 0.73 | ITGB3 (0.34) | TMPRSS6 | |
| SCHEMBL7848502 | 0.73 | ITGB3 (0.40) | F2 | |
| SCHEMBL7847593 | 0.72 | ITGB3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |