Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093422 | 0.95 | ITGB3 (0.34) | ITGB3ITGA2BBDKRB1ALDH1A1MEN1 | |
| SCHEMBL9093450 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2BKDM1A | |
| SCHEMBL9093248 | 0.82 | ITGB3 (0.34) | ITGB3ITGA2BALDH1A1MEN1CYP2C9 | |
| SCHEMBL9093633 | 0.80 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL9093355 | 0.76 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9093375 | 0.75 | ITGB3 (0.33) | ITGB3ITGA2BBDKRB1 | |
| SCHEMBL9093470 | 0.75 | HPN (0.33) | ALDH1A1MEN1CYP2C9KMT2A | |
| SCHEMBL9233938 | 0.73 | HPN (0.35) | ITGB3ITGA2B | |
| SCHEMBL27419936 | 0.70 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL9091922 | 0.68 | ITGB3 (0.34) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |