Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 10/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | HPN | P05981 | 3/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ITGAM | P11215 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233938 | 0.84 | HPN (0.35) | ITGB3ITGA2BF2TMPRSS6PLAU | |
| SCHEMBL9093391 | 0.80 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL9093620 | 0.79 | F2 (0.37) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9091922 | 0.79 | ITGB3 (0.34) | ITGB3ITGA2BTMPRSS6ITGB2ITGAM | |
| SCHEMBL9093422 | 0.78 | ITGB3 (0.34) | ITGB3ITGA2B | |
| SCHEMBL9093470 | 0.78 | HPN (0.33) | PLAUHPN | |
| SCHEMBL9093355 | 0.77 | MEN1 (0.33) | F2PRSS1 | |
| SCHEMBL9095129 | 0.77 | ITGB3 (0.35) | ITGB3ITGA2BF2ITGB2ITGAM | |
| SCHEMBL7790872 | 0.73 | ITGB3 (0.45) | ITGB3ITGA2BITGB2ITGAM | |
| SCHEMBL7790913 | 0.73 | ITGB3 (0.45) | ITGB3ITGA2BITGB2ITGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |