Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9097121 | 0.86 | ADRB2 (0.36) | ADRB2TSHRMAPK1NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL9236348 | 0.81 | ADRB2 (0.37) | ADRB2NFKB1NFKB2RELA | |
| SCHEMBL9097387 | 0.80 | ADRB2 (0.41) | ADRB2TSHR | |
| SCHEMBL9096487 | 0.80 | ADRB2 (0.36) | ADRB2TSHRNFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL9094189 | 0.80 | ADRB2 (0.36) | ADRB2NFKB1NFKB2RELA | |
| SCHEMBL9095407 | 0.80 | ADRB2 (0.36) | ADRB2MAPK1 | |
| Hydrochloric Acid SCHEMBL9094427 | 0.79 | ADRB2 (0.36) | ADRB2 | |
| SCHEMBL9236880 | 0.78 | ADRB2 (0.38) | ADRB2BUB1TSHRNFKB1NFKB2 | |
| SCHEMBL9095909 | 0.77 | ADRB2 (0.38) | ADRB2NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL9232047 | 0.77 | ADRB2 (0.38) | ADRB2BUB1TSHRNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |