Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095139 | 0.90 | MEN1 (0.38) | MAPTMEN1KMT2APOLBRECQL | |
| SCHEMBL9094619 | 0.70 | MEN1 (0.33) | MAPTMEN1KMT2AHCAR3HCAR2 | |
| SCHEMBL10180847 | 0.64 | HCAR3 (0.33) | HCAR3HCAR2 | |
| SCHEMBL9094857 | 0.62 | CYP1A2 (0.41) | MAPTMEN1KMT2A | |
| SCHEMBL18782704 | 0.61 | CYP19A1 (0.37) | — | |
| SCHEMBL13688430 | 0.58 | CYP19A1 (0.45) | ALDH1A1 | |
| SCHEMBL13228149 | 0.56 | PTPN1 (0.47) | ALDH1A1 | |
| SCHEMBL14075281 | 0.55 | KMT2A (0.52) | MAPTKMT2APOLBRECQLALDH1A1 | |
| SCHEMBL8425192 | 0.55 | KDM4E (0.47) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL64965 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |