Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192292 | 0.81 | ALOX5 (0.65) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL31435208 | 0.81 | ALOX5 (0.65) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL31191632 | 0.81 | ALOX5 (0.65) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL976269 | 0.81 | ALOX5 (0.64) | ALOX5MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL9094478 | 0.79 | MAPT (0.51) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL31191627 | 0.78 | ALOX5 (0.65) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL28993863 | 0.78 | ALOX5 (0.65) | ALOX5HTR2BMAPTMEN1KMT2A | |
| SCHEMBL9094472 | 0.76 | ACVR1 (0.64) | PDPK1EGFRMAPTMEN1KMT2A | |
| SCHEMBL17988251 | 0.73 | MAPT (0.48) | ALOX5EGFRTYRMAPTMEN1 | |
| SCHEMBL9092659 | 0.73 | ALOX5 (0.41) | ALOX5HTR2BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029316-A1 | NEW SULFONE ESTER ANALOGUES OF iso-CLOZAPINE AND RELATED STRUCTURES: ATYPICAL NEUROLEPTICS | WIKSTROEM HAAKAN (NL) | 1996-09-26 | — | — | WO | disclosed |