Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988251 | 0.84 | MAPT (0.48) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL380110 | 0.81 | ALOX5 (0.61) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6304472 | 0.81 | MAPT (0.51) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL34463193 | 0.81 | MAPT (0.51) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29753145 | 0.81 | LMNA (0.61) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23515013 | 0.81 | MAPT (0.51) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1367799 | 0.81 | MAPT (0.51) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9967368 | 0.81 | LMNA (0.61) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL31191627 | 0.80 | ALOX5 (0.65) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28993863 | 0.80 | ALOX5 (0.65) | MAPTTDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029316-A1 | NEW SULFONE ESTER ANALOGUES OF iso-CLOZAPINE AND RELATED STRUCTURES: ATYPICAL NEUROLEPTICS | WIKSTROEM HAAKAN (NL) | 1996-09-26 | — | — | WO | disclosed |