Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094905 | 0.84 | DRD4 (0.64) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9095908 | 0.83 | DRD2 (0.62) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096134 | 0.83 | DRD2 (0.62) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9097905 | 0.81 | DRD2 (0.62) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096312 | 0.81 | DRD2 (0.62) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096977 | 0.81 | DRD2 (0.65) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9097217 | 0.81 | DRD2 (0.58) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096047 | 0.81 | DRD2 (0.58) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096389 | 0.80 | DRD2 (0.83) | DRD2DRD4DRD3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9098451 | 0.80 | DRD4 (0.61) | DRD2DRD4DRD3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |
| EP-0624156-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Astra Aktiebolag (SE) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993012085-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | AKTIEBOLAGET ASTRA (SE) | 1993-06-24 | — | — | WO | disclosed |