Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096474 | 1.00 | HPGD (0.40) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8429740 | 0.81 | HPGD (0.36) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8429734 | 0.81 | HPGD (0.36) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8429514 | 0.78 | PKM (0.38) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8429517 | 0.78 | PKM (0.38) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9096478 | 0.78 | PKM (0.38) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7962839 | 0.75 | HPGD (0.47) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7962836 | 0.75 | HPGD (0.47) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7962841 | 0.75 | HPGD (0.47) | HPGDPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8425871 | 0.75 | PPME1 (0.39) | HPGDPKML3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040675-A1 | THIENYL COMPOUNDS FOR INHIBITION OF CELL PROLIFERATIVE DISORDERS | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040675-A1 | THIENYL COMPOUNDS FOR INHIBITION OF CELL PROLIFERATIVE DISORDERS | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |