Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9095255 | 0.99 | ADRB2 (0.34) | ADRB2NQO2KDM4EALDH1A1GLA | |
| SCHEMBL9097311 | 0.88 | ADRB2 (0.33) | ADRB2NQO2 | |
| Hydrochloric Acid SCHEMBL9096266 | 0.87 | ADRB2 (0.33) | ADRB2NQO2 | |
| SCHEMBL9095353 | 0.86 | ADRB2 (0.37) | ADRB2NQO2KDM4EALDH1A1GLA | |
| SCHEMBL9094037 | 0.86 | ADRB2 (0.38) | ADRB2NQO2KDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL9095455 | 0.85 | ADRB2 (0.38) | ADRB2NQO2KDM4EALDH1A1GLA | |
| SCHEMBL9095756 | 0.84 | SIRT2 (0.36) | ADRB2NQO2KDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL9096376 | 0.83 | SIRT2 (0.36) | ADRB2NQO2KDM4EALDH1A1GLA | |
| SCHEMBL9094055 | 0.81 | ADRB2 (0.38) | ADRB2NQO2KDM4EALDH1A1GLA | |
| SCHEMBL9094138 | 0.81 | ADRB2 (0.40) | ADRB2NQO2KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |