Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | AQP1 | P29972 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9095455 | 0.99 | ADRB2 (0.38) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9095756 | 0.88 | SIRT2 (0.36) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9094055 | 0.87 | ADRB2 (0.38) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9094138 | 0.87 | ADRB2 (0.40) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9096420 | 0.87 | ADRB2 (0.38) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9097351 | 0.87 | ADRB2 (0.38) | ADRB2KDM4EALDH1A1GLAGAA | |
| Hydrochloric Acid SCHEMBL9096376 | 0.87 | SIRT2 (0.36) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9096329 | 0.86 | AQP1 (0.43) | ADRB2KDM4EALDH1A1GLAGAA | |
| SCHEMBL9097332 | 0.86 | ADRB2 (0.35) | ADRB2KDM4EALDH1A1GLAGAA | |
| Hydrochloric Acid SCHEMBL9094266 | 0.85 | ADRB2 (0.38) | ADRB2KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |