Glyoxylate

Glyoxylate

SCHEMBL909798

O=CC(=O)O.c1ccoc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 1/20 0.35
HCAR2 Q8TDS4 2/20 0.32
TSHR P16473 2/20 0.30
TP53 P04637 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EGLN3 Q9H6Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL27334511 0.82 TSHR (0.53) MAPK1TDP1ALDH1A1HCAR2TSHR
Maleic Acid SCHEMBL20377191 0.82 TSHR (0.53) MAPK1TDP1ALDH1A1HCAR2TSHR
Maleic Acid SCHEMBL11672612 0.82 TSHR (0.53) MAPK1TDP1ALDH1A1HCAR2TSHR
Furan SCHEMBL5278070 0.81 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL27656052 0.81 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL7296766 0.81
Benzene SCHEMBL4653866 0.80 ALDH1A1 (0.45) MAPK1TDP1ALDH1A1HCAR2TSHR
Acrylic Acid SCHEMBL29006811 0.80 LMNA (0.56) MAPK1TDP1ALDH1A1HCAR2TSHR
Acrylic Acid SCHEMBL3048137 0.80 LMNA (0.56) MAPK1TDP1ALDH1A1HCAR2TSHR
Oxalic Acid SCHEMBL7279431 0.78 MAPK1 (0.57) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590719-B Green method for preparing 2-furoic acid 安徽金禾实业股份有限公司 2022-04-19 CN disclosed
CN-110590719-A Green method for preparing 2-furoic acid 安徽金禾实业股份有限公司 2019-12-20 CN disclosed
CN-109160908-A A kind of synthetic method of 2- methoxy imino -2- furans acetic acid 四平市精细化学品有限公司 2019-01-08 CN disclosed
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US disclosed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US disclosed
CN-101538255-B Preparing method of 2-methoxy imino group 2-furan ammonium acetate ZHEJIANG TOP MEDICINE CO LTD 2011-07-20 CN disclosed
US-20110021740-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2011-01-27 US disclosed
CN-101538255-A Preparing method of 2-methoxy imino group 2-furan ammonium acetate ZHEJIANG TOP MEDICINE CO LTD 2009-09-23 CN disclosed
US-6048852-A BACTERICIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-04-11 US disclosed
EP-0900197-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1999-03-10 EP disclosed
WO-1997030027-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1997-08-21 WO disclosed