Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232172 | 0.93 | ALOX5 (0.68) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9099705 | 0.84 | ALOX5 (0.71) | ALOX5CYP11B2 | |
| SCHEMBL9088351 | 0.83 | ALOX5 (0.72) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL8554746 | 0.78 | ALOX5 (0.73) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9088453 | 0.78 | ALOX5 (0.65) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9126763 | 0.76 | ALOX5 (0.70) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9282610 | 0.73 | ALOX5 (0.55) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9099749 | 0.73 | ALOX5 (0.55) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9282601 | 0.73 | ALOX5 (0.55) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 | |
| SCHEMBL9282605 | 0.73 | ALOX5 (0.55) | ALOX5CYP11B2TRIM24CYP1A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702680-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029297-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |