Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110042 | 0.89 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9100476 | 0.88 | ALOX5 (0.58) | ALOX5CYP11B2 | |
| SCHEMBL9280770 | 0.88 | ALOX5 (0.58) | ALOX5CYP11B2 | |
| SCHEMBL9280765 | 0.88 | ALOX5 (0.58) | ALOX5CYP11B2 | |
| SCHEMBL9280772 | 0.88 | ALOX5 (0.58) | ALOX5CYP11B2 | |
| SCHEMBL9275052 | 0.87 | ALOX5 (0.58) | ALOX5CYP11B2 | |
| SCHEMBL9203502 | 0.85 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9198033 | 0.84 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL9232172 | 0.84 | ALOX5 (0.68) | ALOX5CYP11B2 | |
| SCHEMBL9098375 | 0.84 | ALOX5 (0.68) | ALOX5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485111-A2 | The use of lipoxygenase and cyclooxygenase inhibitors as synergistic agents | ZENECA LIMITED (GB) | 1992-05-13 | — | — | EP | claimed |
| EP-0702678-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| EP-0702680-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995030668-A1 | CYCLIC ETHER DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ZENECA LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |
| EP-0466452-B1 | Thioxo heterocycles and their pharmaceutical use | ZENECA LTD (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994029297-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994029291-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |
| US-5240941-A | Enzyme inhibitors; antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-08-31 | — | — | US | disclosed |
| EP-0485111-A2 | The use of lipoxygenase and cyclooxygenase inhibitors as synergistic agents | ZENECA LIMITED (GB) | 1992-05-13 | — | — | EP | disclosed |
| EP-0466452-A2 | Thioxo heterocycles and their pharmaceutical use | ZENECA LIMITED (GB) | 1992-01-15 | — | — | EP | disclosed |