Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568359 | 0.85 | ME2 (0.67) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL22777865 | 0.83 | MAPT (1.00) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5904008 | 0.82 | MAPT (0.75) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9568295 | 0.81 | MAPT (0.73) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6074555 | 0.81 | MAPT (0.73) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31715873 | 0.80 | NAMPT (0.64) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2867356 | 0.80 | AKR1C3 (0.69) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10981623 | 0.80 | ME2 (0.64) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL12916359 | 0.78 | HTT (0.59) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2878977 | 0.78 | POLB (0.69) | MAPTLMNASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026923-A1 | NOVEL BI-TRYPTAMINIC DERIVATIVES, PREPARATION PROCESS AND UTILIZATION AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-09-06 | — | — | WO | disclosed |