Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 2/20 | 0.67 |
| ▸ | ME1 | P48163 | 2/20 | 0.67 |
| ▸ | ME3 | Q16798 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099028 | 0.85 | MAPT (0.71) | MAPTKMT2AMEN1POLBMAPK1 | |
| SCHEMBL9568418 | 0.84 | KMT2A (0.64) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL9568295 | 0.83 | MAPT (0.73) | MAPTKMT2AMEN1POLBMAPK1 | |
| SCHEMBL2767151 | 0.81 | ME2 (1.00) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL11076871 | 0.79 | GFER (0.89) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL29967184 | 0.79 | MAPT (0.70) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL10902216 | 0.79 | GFER (0.78) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL27022350 | 0.78 | MAPT (0.71) | MAPTKMT2AMEN1GFERMAPK1 | |
| SCHEMBL2867356 | 0.77 | AKR1C3 (0.69) | ME2ME1ME3MAPTKMT2A | |
| SCHEMBL22777865 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1GFERPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524146-A1 | Aminosubstituted Piperazinederivatives | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |