Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142984 | 0.85 | L3MBTL1 (0.59) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7043026 | 0.83 | POLB (0.62) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1252896 | 0.81 | KMT2A (0.59) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL977842 | 0.81 | PTGDR2 (0.60) | CYP17A1MEN1KMT2ASMN1; SMN2PTGDR2 | |
| SCHEMBL2690874 | 0.80 | MAPT (0.48) | MEN1KMT2ASMN1; SMN2SYKMAPT | |
| SCHEMBL7955791 | 0.80 | CYP17A1 (0.57) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16693228 | 0.80 | CYP17A1 (0.51) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4143456 | 0.80 | CYP17A1 (0.51) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14861108 | 0.79 | CYP17A1 (0.52) | CYP17A1MEN1KMT2APTGDR2PPARG | |
| SCHEMBL3182565 | 0.79 | NAMPT (0.57) | CYP17A1MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510831-B1 | Low molecular weight monoalkyl phosphinate and phosphonate copolymers | ROHM & HAAS (US) | 1996-06-12 | — | — | EP | claimed |
| US-5527524-A | AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1988001180-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |