Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097511 | 0.95 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL9280944 | 0.93 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL8908562 | 0.93 | PRKAB2 (0.48) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL8907217 | 0.93 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL8908739 | 0.93 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL8908328 | 0.93 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL8907044 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL9097388 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL9097665 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL9282050 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNATP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |