Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396303 | 0.92 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL29458124 | 0.92 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL29769084 | 0.82 | MAPT (0.62) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL3442514 | 0.82 | MAPT (0.62) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL15649292 | 0.78 | CHRNB2 (0.50) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL4548252 | 0.78 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EGAAMAPT | |
| SCHEMBL5509909 | 0.78 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL1663340 | 0.77 | CYP19A1 (0.59) | KDM4ERAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5275797 | 0.77 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4EGAARAB9A | |
| SCHEMBL7399032 | 0.77 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006079-A1 | BIPHENYLAMIDE DERIVATIVES AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-02-29 | — | — | WO | disclosed |