Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097135 | 0.79 | NCF1 (0.41) | MYCWDR5ALDH1A1KDM4EMEN1 | |
| SCHEMBL211069 | 0.75 | EHMT2 (0.44) | MYCWDR5ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9047937 | 0.74 | L3MBTL1 (0.45) | MYCWDR5ALDH1A1KDM4EMEN1 | |
| SCHEMBL9096078 | 0.72 | MAPT (0.44) | MYCWDR5ALDH1A1LMNAKDM4E | |
| SCHEMBL1607000 | 0.71 | MYC (0.48) | MYCWDR5ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL28443457 | 0.70 | SMN1; SMN2 (0.45) | MYCWDR5ALDH1A1LMNAKDM4E | |
| SCHEMBL9098198 | 0.70 | MYC (0.59) | MYCWDR5ALDH1A1MAPTALOX15 | |
| SCHEMBL9099767 | 0.69 | BACE1 (0.46) | MYCWDR5ALDH1A1LMNAKDM4E | |
| SCHEMBL9097754 | 0.69 | BACE1 (0.46) | MYCWDR5ALDH1A1LMNAKDM4E | |
| SCHEMBL9099215 | 0.69 | HPGD (0.54) | MYCWDR5ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030370-A2 | THIAZOLE AND THIADIAZOLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF THROMBOCYTOPENIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |