Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071727 | 0.87 | SMN1; SMN2 (0.46) | ERN1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL2479195 | 0.82 | ERN1 (0.55) | ERN1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL1070965 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9099491 | 0.77 | ERN1 (0.47) | ERN1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL537223 | 0.76 | ERN1 (0.62) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL192836 | 0.76 | ERN1 (0.62) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11638782 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL4361452 | 0.75 | ERN1 (0.47) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10688420 | 0.74 | SIRT6 (0.48) | ERN1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL3420384 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | claimed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | claimed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |