Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358711 | 0.86 | ALDH1A1 (0.47) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10688420 | 0.79 | SIRT6 (0.48) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16635495 | 0.77 | BRAF (0.47) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22123094 | 0.77 | ERN1 (0.55) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9475477 | 0.77 | ERN1 (0.51) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9099498 | 0.77 | ERN1 (0.49) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27797779 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9754355 | 0.76 | ALDH1A1 (0.40) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8421994 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL27869238 | 0.76 | SMN1; SMN2 (0.43) | ERN1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | claimed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | claimed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |