Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786341 | 0.89 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL5586458 | 0.89 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL775333 | 0.87 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL28663547 | 0.83 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL1960709 | 0.82 | MAPT (0.65) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL28489934 | 0.82 | MEN1 (0.83) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14422990 | 0.81 | MEN1 (0.82) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12179667 | 0.80 | PDGFRB (0.59) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL9098509 | 0.80 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2APDGFRB | |
| SCHEMBL6782503 | 0.80 | PDGFRB (0.54) | NPC1RAB9AMEN1KMT2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5507974-A | FOR NONLINEAR OPTICAL APPLICATIONS; FREQUENCY DOUBLING OF LIGHT | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |