SCHEMBL775333

SCHEMBL775333

c1cc(-c2cnc(-c3ccncc3)nc2)ccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.61
RAB9A P51151 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
NFKB1 P19838 2/20 0.61
NFKB2 Q00653 2/20 0.61
RELA Q04206 2/20 0.61
MAPT P10636 3/20 0.58
LMNA P02545 1/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
HSD17B10 Q99714 1/20 0.56
PDGFRB P09619 8/20 0.50
PDGFRA P16234 8/20 0.50
HPGDS O60760 1/20 0.50
NOTUM Q6P988 1/20 0.48
EGFR P00533 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786341 0.97 NPC1 (0.60) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL14964814 0.91 SMN1; SMN2 (0.78) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL27550563 0.87 NPC1 (0.51) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL6782503 0.87 PDGFRB (0.54) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9099501 0.87 NPC1 (0.80) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9098395 0.87 NPC1 (0.80) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9098509 0.87 NPC1 (0.80) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9099431 0.82 CLK4 (0.61) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9101997 0.82 NPC1 (0.50) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL9099848 0.82 CLK4 (0.61) NPC1RAB9ASMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907388-A Synthesis of three-dimensional microporous cadmium compound and application of three-dimensional microporous cadmium compound in pesticide residue pymetrozine detection 皖西学院 2022-08-16 CN claimed
EP-2435531-B1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT SIEMENS AG (DE) 2013-10-30 EP claimed
US-20120069419-A1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT SIEMENS AKTIENGESELLSCHAFT (DE) 2012-03-22 US claimed
CN-119751903-A Three-dimensional microporous cadmium complex with active site and preparation method and application thereof 皖西学院 2025-04-04 CN disclosed
CN-114907388-B Synthesis of three-dimensional microporous cadmium compound and application of three-dimensional microporous cadmium compound in pesticide residue pymetrozine detection 皖西学院 2023-10-10 CN disclosed
CN-114907388-A Synthesis of three-dimensional microporous cadmium compound and application of three-dimensional microporous cadmium compound in pesticide residue pymetrozine detection 皖西学院 2022-08-16 CN disclosed
EP-2652810-B9 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-11-10 EP disclosed
EP-2652810-B1 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-08-11 EP disclosed
US-20200203609-A1 Radiation-Emitting Organic-Electronic Device and Method for Producing a Radiation-Emitting Organic-Electronic Device OSRAM OLED GMBH (DE) 2020-06-25 US disclosed
EP-3268448-B1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC ELEMENT, AND ELECTROCHROMIC DIMMING ELEMENT RICOH CO LTD (JP) 2020-06-03 EP disclosed
US-10615346-B2 Radiation-emitting organic-electronic device and method for producing a radiation-emitting organic-electronic device OSRAM OLED GMBH (DE) 2020-04-07 US disclosed
US-8558223-B2 Organic electronic component and method for the production thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2013-10-15 US disclosed
US-8558223-B2 Organic electronic component and method for the production thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2013-10-15 US disclosed
US-20120286253-A1 Organic Electronic Device and Method for the Production Thereof OSRAM OLED GMBH (DE) 2012-11-15 US disclosed
US-20120286253-A1 Organic Electronic Device and Method for the Production Thereof OSRAM OLED GMBH (DE) 2012-11-15 US disclosed
US-20120069418-A1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT SIEMENS AKTIENGESELLSCHAFT (DE) 2012-03-22 US disclosed
US-20120069419-A1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT SIEMENS AKTIENGESELLSCHAFT (DE) 2012-03-22 US disclosed
WO-2011039323-A2 ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2011-04-07 WO disclosed
WO-2010034304-A2 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-04-01 WO disclosed
US-5507974-A FOR NONLINEAR OPTICAL APPLICATIONS; FREQUENCY DOUBLING OF LIGHT HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120069418-A1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT HCN2, EPX, HCN4 NPC1 4367/4885RAB9A 2138/4885SMN1; SMN2 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.