SCHEMBL12786341

SCHEMBL12786341

c1cc(-c2ncc(-c3ccc(-c4cnc(-c5ccncc5)nc4)cc3)cn2)ccn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.60
RAB9A P51151 5/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 4/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 1/20 0.60
TP53 P04637 1/20 0.60
HPGD P15428 1/20 0.60
HSD17B10 Q99714 1/20 0.60
NFKB1 P19838 2/20 0.58
NFKB2 Q00653 2/20 0.58
RELA Q04206 2/20 0.58
LMNA P02545 1/20 0.55
HPGDS O60760 1/20 0.49
PDGFRB P09619 6/20 0.48
PDGFRA P16234 6/20 0.48
NOTUM Q6P988 1/20 0.46
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775333 0.97 NPC1 (0.61) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL27550563 0.89 NPC1 (0.51) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9099501 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9098395 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9098509 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL6782503 0.89 PDGFRB (0.54) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL14964814 0.89 SMN1; SMN2 (0.78) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9101997 0.84 NPC1 (0.50) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9099431 0.84 CLK4 (0.61) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL9099848 0.84 CLK4 (0.61) NPC1RAB9ASMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2652810-B9 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-11-10 EP disclosed
EP-2652810-B1 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-08-11 EP disclosed
US-20200203609-A1 Radiation-Emitting Organic-Electronic Device and Method for Producing a Radiation-Emitting Organic-Electronic Device OSRAM OLED GMBH (DE) 2020-06-25 US disclosed
US-10615346-B2 Radiation-emitting organic-electronic device and method for producing a radiation-emitting organic-electronic device OSRAM OLED GMBH (DE) 2020-04-07 US disclosed
US-10454050-B2 Organic light-emitting device OSRAM OLED GMBH (DE) 2019-10-22 US disclosed
US-9735397-B2 Radiation-emitting organic-electronic device and method for the production thereof OSRAM OLED GMBH (DE) 2017-08-15 US disclosed
US-9520570-B2 Organic electronic device and method for the production thereof OSRAM OLED GMBH (DE) 2016-12-13 US disclosed
US-9520570-B2 Organic electronic device and method for the production thereof OSRAM OLED GMBH (DE) 2016-12-13 US disclosed
EP-2483945-B1 ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF OSRAM OLED GMBH (DE) 2016-11-02 EP disclosed
US-20160079536-A1 Radiation-Emitting Organic-Electronic Device and Method for Producing a Radiation-Emitting Organic-Electronic Device DOLYA HOLDCO 5 LIMITED (IE) 2016-03-17 US disclosed
EP-2342772-B1 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF OSRAM OLED GMBH (DE) 2015-12-02 EP disclosed
US-20150076451-A1 ORGANIC LIGHT-EMITTING COMPONENT DOLYA HOLDCO 5 LIMITED (IE) 2015-03-19 US disclosed
US-20150034930-A1 ORGANIC LIGHT-EMITTING DEVICE OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2015-02-05 US disclosed
US-20140014931-A1 RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2014-01-16 US disclosed
US-8558223-B2 Organic electronic component and method for the production thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2013-10-15 US disclosed
US-8558223-B2 Organic electronic component and method for the production thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2013-10-15 US disclosed
US-20120286253-A1 Organic Electronic Device and Method for the Production Thereof OSRAM OLED GMBH (DE) 2012-11-15 US disclosed
US-20120286253-A1 Organic Electronic Device and Method for the Production Thereof OSRAM OLED GMBH (DE) 2012-11-15 US disclosed
WO-2011039323-A2 ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2011-04-07 WO disclosed
WO-2010034304-A2 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-04-01 WO disclosed