SCHEMBL39571

SCHEMBL39571

CCCCc1c(O)cc(O)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.50
HTT P42858 2/20 0.50
PPARA Q07869 2/20 0.50
NPC1 O15118 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PTPN1 P18031 2/20 0.47
PTPN11 Q06124 1/20 0.47
KDM4E B2RXH2 2/20 0.46
PKM P14618 1/20 0.46
TYR P14679 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Grevillol SCHEMBL31345744 0.93 KAT8 (0.59) KAT8HTTPPARAPTPN1PTPN11
SCHEMBL39033 0.89 PTPN1 (0.54) KAT8PPARAPTPN1PTPN11KDM4E
SCHEMBL9099516 0.84 KAT8 (0.55) KAT8PPARACYP3A4HCAR2PPARG
SCHEMBL22660353 0.83 CA12 (0.40) KAT8PPARAPTPN1PTPN11CYP3A4
SCHEMBL19433123 0.82 CA12 (0.47) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL39025 0.82 CA12 (0.45) KAT8PPARAHPGDPTPN1PTPN11
SCHEMBL29130838 0.81 KAT8 (0.49) KAT8HTTPPARANPC1HPGD
SCHEMBL9743295 0.81 HTT (0.72) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL45169 0.79 KAT8 (0.46) KAT8HTTPPARANPC1HPGD
SCHEMBL27607961 0.78 GABRP (0.46) KAT8HTTPPARANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 CN disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 US disclosed
US-20190125052-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-05-02 US disclosed
US-20180353406-A1 AGENT FOR HAIR DEFORMING TREATMENT KAO CORPORATION (JP) 2018-12-13 US disclosed
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT KAO CORPORATION (JP) 2018-11-01 US disclosed
WO-2017207767-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 WO disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
CN-106999380-A Hair deforming agent 花王株式会社 2017-08-01 CN disclosed
CN-106999382-A Hair deformation process agent 花王株式会社 2017-08-01 CN disclosed
EP-2584896-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2013-05-01 EP disclosed
US-20130102463-A1 Herbicidal Compositions BASF SE (DE) 2013-04-25 US disclosed
WO-2011161105-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2011-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C KAT8 53/4885HTT 46/4885PPARA 351/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR KAT8 45/4885HTT 137/4885PPARA 117/4885
US-20180353406-A1 AGENT FOR HAIR DEFORMING TREATMENT GRHPR, SLC26A4, COL1A1 KAT8 2156/4885HTT 208/4885PPARA 2550/4885
US-20130102463-A1 Herbicidal Compositions PPOX, PAOX, DDT KAT8 3725/4885HTT 856/4885PPARA 804/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR KAT8 45/4885HTT 137/4885PPARA 117/4885
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT COL1A1, COL2A1, GRHPR KAT8 1047/4885HTT 240/4885PPARA 1685/4885
US-20190125052-A1 METHOD FOR TREATING HAIR GRHPR, TYR, POLR1C KAT8 287/4885HTT 433/4885PPARA 648/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C KAT8 53/4885HTT 46/4885PPARA 351/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 KAT8 2156/4885HTT 208/4885PPARA 2550/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR KAT8 90/4885HTT 136/4885PPARA 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.