SCHEMBL9099547

SCHEMBL9099547

CC(Cc1ccc(S(=O)(=O)O)cc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP2D6 P10635 2/20 0.44
MAPK1 P28482 1/20 0.44
POLB P06746 1/20 0.43
ALDH1A1 P00352 3/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 1/20 0.42
HDAC1 Q13547 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
SCN3A Q9NY46 1/20 0.41
LMNA P02545 1/20 0.41
NR3C2 P08235 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MMP2 P08253 2/20 0.40
MMP9 P14780 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18052665 0.83 TSHR (0.52) TSHRSMN1; SMN2CYP2D6MAPK1POLB
SCHEMBL9069704 0.82 ESR1 (0.61) ESR1ESR2TAAR1
SCHEMBL6266176 0.78 ALDH1A1 (0.58) ESR1TSHRSMN1; SMN2ALDH1A1LMNA
SCHEMBL8983689 0.78 TAAR1 (0.56) ESR1ESR2CYP2D6SCN3ATAAR1
SCHEMBL535702 0.78 TAAR1 (0.56) ESR1ESR2CYP2D6SCN3ATAAR1
SCHEMBL14799062 0.78 TAAR1 (0.56) ESR1ESR2CYP2D6SCN3ATAAR1
SCHEMBL26635070 0.78 TSHR (0.46) TSHRSMN1; SMN2CYP2D6MAPK1POLB
SCHEMBL26635021 0.78 TSHR (0.46) TSHRSMN1; SMN2CYP2D6MAPK1POLB
SCHEMBL26635047 0.78 TSHR (0.46) TSHRSMN1; SMN2CYP2D6MAPK1POLB
SCHEMBL27602760 0.78 TSHR (0.41) ESR1ESR2TSHRSMN1; SMN2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489501-A MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES RICOH COMPANY, LTD. (JP) 1996-02-06 US disclosed