Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.63 |
| ▸ | TSHR | P16473 | 11/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69390 | 0.82 | HSD17B10 (0.65) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL70073 | 0.82 | HSD17B10 (0.72) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL29262426 | 0.79 | HSD17B10 (0.46) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL134043 | 0.79 | HSD17B10 (0.50) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL30631745 | 0.79 | HSD17B10 (0.77) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL11832897 | 0.79 | HSD17B10 (0.77) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| Triclofenol SCHEMBL28856638 | 0.78 | HSD17B10 (0.74) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL827930 | 0.78 | HSD17B10 (1.00) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL11879785 | 0.77 | HSD17B10 (0.57) | HSD17B10TSHRHPGDCASP1CYP3A4 | |
| SCHEMBL11234833 | 0.77 | HSD17B10 (0.57) | HSD17B10TSHRHPGDCASP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512478-A | PURIFIED DNA MOLECULES ENCODING PROTEIN ENZYMES; BIOREMEDIATION | IDAHO RESEARCH FOUNDATION, INC. (US) | 1996-04-30 | — | — | US | disclosed |
| US-5364787-A | Genes and enzymes involved in the microbial degradation of pentachlorophenol | IDAHO RESEARCH FOUNDATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| WO-1993019169-A1 | GENES AND ENZYMES INVOLVED IN THE MICROBIAL DEGRADATION OF PENTACHLOROPHENOL | IDAHO RESEARCH FOUNDATION, INC. (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |
| US-3987109-A | POLYMERIZATION OF POLYFUNCTIONAL PHENOLS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-10-19 | — | — | US | disclosed |