Triclofenol

Triclofenol

SCHEMBL28856638

Oc1c(Cl)c(Cl)cc(Cl)c1Cl.Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 12/20 0.74
TSHR P16473 10/20 0.74
HPGD P15428 8/20 0.74
CASP1 P29466 1/20 0.74
CYP3A4 P08684 6/20 0.52
MAPK1 P28482 3/20 0.52
HSP90AA1 P07900 2/20 0.52
MEN1 O00255 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
RECQL P46063 2/20 0.44
NPC1 O15118 1/20 0.44
USP2 O75604 1/20 0.44
EGFR P00533 1/20 0.44
ESR1 P03372 1/20 0.44
ERBB2 P04626 1/20 0.44
CYP1A2 P05177 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL9036678 0.90 HSD17B10 (0.74) HSD17B10TSHRHPGDCASP1CYP3A4
Triclofenol SCHEMBL1338 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDCASP1CYP3A4
Triclofenol SCHEMBL29387498 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL827930 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL70073 0.83 HSD17B10 (0.72) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL28190361 0.83 HSD17B10 (0.93) HSD17B10TSHRHPGDCASP1CYP3A4
Triclofenol SCHEMBL2813598 0.83 HSD17B10 (0.93) HSD17B10TSHRHPGDCASP1CYP3A4
Pentachlorophenol SCHEMBL29158480 0.80 HSD17B10 (0.88) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL48305 0.80 HSD17B10 (0.86) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL9099561 0.78 HSD17B10 (0.63) HSD17B10TSHRHPGDCASP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115190901-A Carbodiimide composition, curing agent composition, coating composition, and resin cured product 旭化成株式会社 2022-10-14 CN disclosed