SCHEMBL70073

SCHEMBL70073

Oc1cc(Cl)c(Cl)c(O)c1Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 12/20 0.72
TSHR P16473 11/20 0.72
HPGD P15428 8/20 0.72
CASP1 P29466 1/20 0.72
CYP3A4 P08684 7/20 0.65
HSP90AA1 P07900 2/20 0.65
ALDH1A1 P00352 5/20 0.55
MAPK1 P28482 3/20 0.50
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
RECQL P46063 2/20 0.42
THRB P10828 2/20 0.42
CYP1A2 P05177 2/20 0.42
ALOX15 P16050 2/20 0.42
ALOX12 P18054 2/20 0.42
CYP2C19 P33261 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11882357 0.84 HSD17B10 (0.56) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL827930 0.84 HSD17B10 (1.00) HSD17B10TSHRHPGDCASP1CYP3A4
Pentachlorophenol SCHEMBL10591274 0.83 HSD17B10 (0.84) HSD17B10TSHRHPGDCASP1CYP3A4
Triclofenol SCHEMBL28856638 0.83 HSD17B10 (0.74) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL9099561 0.82 HSD17B10 (0.63) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL11234833 0.82 HSD17B10 (0.57) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL28190361 0.81 HSD17B10 (0.93) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL1259609 0.81 HSD17B10 (0.70) HSD17B10TSHRHPGDCASP1CYP3A4
SCHEMBL202648 0.79 HSD17B10 (1.00) HSD17B10TSHRHPGDCASP1CYP3A4
Pentachlorophenol SCHEMBL29158480 0.79 HSD17B10 (0.88) HSD17B10TSHRHPGDCASP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104955585-B Preservative application member 开尔弗森2200有限公司 2018-04-13 CN disclosed
CN-103338732-A Feminine care absorbent article for use in warm climates KIMBERLY CLARK CO 2013-10-02 CN disclosed
CN-101942498-B Kit for rapidly detecting diabetes UNIV HEBEI AGRICULTURE 2013-04-17 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
CN-102223903-A Medical adhesive composition ETHICON INC 2011-10-19 CN disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
CN-1895672-B Multifunctional broad-spectrum obtundent of polyphyletic synergistic and its use LINXIANG BIOLOG TECHNOLOGY CO LTD SHANGHAI 2011-08-10 CN disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1009729-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-06-21 EP disclosed
US-6005137-A POLYMERS USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-21 US disclosed
WO-1998056749-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-17 WO disclosed
EP-0664014-B1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL NV (NL) 1998-08-19 EP disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed
EP-0664014-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS Akzo Nobel N.V. (NL) 1995-07-26 EP disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US disclosed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP disclosed
US-3988318-A HYDROXY-PHENOLS; PLASTICIZERS GAF CORPORATION (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885TSHR 3263/4885HPGD 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.