Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23571405 | 0.84 | GRM5 (0.37) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL23571406 | 0.81 | TRPA1 (0.37) | MAPTRAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8376019 | 0.81 | PIK3R1 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23293908 | 0.81 | RXFP1 (0.41) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL16378071 | 0.81 | NPC1 (0.37) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| Hydrochloric Acid SCHEMBL16339505 | 0.79 | MAPT (0.36) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL25102741 | 0.78 | TLR9 (0.33) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL26768183 | 0.78 | NPC1 (0.42) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8814047 | 0.77 | SMN1; SMN2 (0.58) | MAPTNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL22291156 | 0.76 | PDE10A (0.36) | MAPTNPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299470-B1 | Imidazo[1,2-a]pyridines | BYK GULDEN LOMBERG CHEM FAB (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5112834-A | Antisecretory and antiulcer | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0370056-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1990-05-30 | — | — | EP | disclosed |
| WO-1989000570-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299470-A1 | Imidazo[1,2-a]pyridines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-01-18 | — | — | EP | disclosed |